Our team offers to customers various methods of detection of cellular and sub-cellular signals usingnon-radioactive technologies.

Here is below in vitro assays available at MBRC:

• Microplate cellular assays

  • Viability and cell proliferation assays

  • Microbial viability assay

  • Inflammation assay

• Microplate sub-cellular assays

  • Enzyme assay

• Amplification and quantification of genes by real-time PCR

• ADME study, including membrane permeability (Papp and efflux measurement) and CYP450 inhibition assays

• Genotoxicity test (bacterial reverse mutationof AMES II™ and AMES MPF™)

• Measurement of antioxidant activity (ORAC)

• Immunocytochemistry with fluorescence

• Genotyping of V Leiden, prothrombin II and MTHFR mutations

• Identification of clonality of IGH, IGK and TCRG

• Bioguided screening of extracts and pure compounds

Furthermore, the MBRC possess its own in-house R&D program for the discovery of value-added molecules derived from marine biomasses.